Treatable Diseases

About

Sepsis is a life-threatening condition that arises when the body’s response to an infection injures its own tissues and organs. It’s a medical emergency that requires immediate attention as it can lead to organ failure and death if not treated promptly.

Early recognition and treatment with antibiotics and fluids are crucial for improving outcomes. Sepsis can affect people of all ages and can result from various infections, including bacterial, viral, or fungal.

Sequence of Events

• Pathogen Invasion: pathogens gain entry to the bloodstream and stick to the inside of the blood vessel
• Blood vessels begin to leak: this causes dissemination of infection into distant organs
• Inflammatory Response: Pathogen binding triggers an exaggerated inflammatory response (cytokine storm)
• Organ Failure and Death: Widespread infection, inflammation and inadequate blood perfusion leads to organ failure and ultimately death.

About

Coronavirus SARS-CoV-2 caused a global pandemic of COVID-19, affecting millions of people worldwide and leading to significant public health, economic, and societal impacts.

It is a respiratory illness caused by the novel coronavirus SARS-CoV-2 and spreads primarily through respiratory droplets from coughs or sneezes of an infected person or by touching contaminated surfaces and then touching the face.

Sequence of Events

• Transmission and replication: SARS-CoV-2 gain entry to the sinonasal airways via respiratory droplets from an infected person.
• Recognition and Activation: New viral particles make their way to the lungs where they attached to the alveolar cells
• Lung injury and ARDS: SARS-CoV-2 binding causes complications like pneumonia and acute respiratory distress syndrome (ARDS) triggering separation of the lung cells
• Inflammatory Response: SARS-CoV-2 triggers an exaggerated inflammatory response (cytokine storm)
• Organ Failure and Death: Widespread infection, inflammation and inadequate blood perfusion leads to organ failure and ultimately death